pentobarbital will lower the level or result of doxorubicin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital decreases consequences of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Coadministration of CYP3A4 inducers may lessen sufentanil de